Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free: https://www.ghostery.com/fr/products/

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site: http://www.youronlinechoices.com/fr/controler-ses-cookies/, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Realytics
Google Analytics
Spoteffects
Optimizely

Targeted advertising cookies

DoubleClick
Mediarithmics

The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at cil-dpo@inra.fr or by post at:

INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal log DGIMI logo EPHE logo UM logo ville ajaccio

Worshop, Parvovirus, Biennial Workshop

XVIth International Parvovirus Workshop

19 - 23 June 2016 Ajaccio Congress Center - Corsica

Sunday 19 June 2016

6:00 pm - 9:00 pm : Registration and Welcome Reception Ajaccio Congress Center

9:00 pm - 10:00 pm : Session 1. Opening session. What’s new with parvoviruses?

Chairpersons: Mylène Ogliastro then Susan Cotmore and Luk Vandenberghe

Monday 20 June 2016

8:30 am - 10:10 am : Session 2A. Diversity and evolution

Chairpersons: Susan Cotmore and Peter Tijssen

  • O-1     Small is beautiful: origin and evolution of eukaryotic single-stranded DNA   viruses

                    Mart Krupovic

  • O-2     Discovery of parvovirus sequences in an unexpected broad range of animals

                    Sarah François, D. Filloux, P. Roumagnac, D. Bigot, P. Gayral, D. Martin, R. Froissart and M. Ogliastro

  • O-3     A novel cricket densovirus is the first parvovirus harboring a segmented genome

                    Judit Penzes, HT. Pham, M. Bergoin and P. Tijssen

  • O-4     Bufavirus and tusavirus – further epidemiological studies with emphasis on serology

                    Elina Väisänen, M. Paloniemi, I. Kuisma, V. Lithovius, A. Kumar, R. Franssila, T. Vesikari, K. Hedman and M. Söderlund-Venermo

10:10 am - 11:00 am : Coffee Break & Poster Session

11:00 am - 12:30 pm : Session 2B. Virus Diversity and Evolution

Chairpersons: Mylène Ogliastro and Jürg Nüesch

  • O-5     Old friend turned fiend? Sea star associated densovirus and wasting disease

                    Ian Hewson, E. Jackson, L. Lahner

  • O-6     Cloning and rescue of the genome of Bombyx mori bidensovirus, and  characterization of a recombinant virus

                    Panpan Zhang, D. Miao, Y. Zhang, M. Wang, Z. Hu, P. Lü and Qi. Yao

  • O-7     Characterization of Bufavirus Capsids

                    S. Kailasan, M. Ilyas, J. Garriso, P. Chipman, R. McKenna, E. Väisänen, M. Söderlund-Venermo, and Mavis Agbandje-McKenna

  • O-8     Serpentine Adeno-Associated Virus (sAAV) conserves the core structure of mammalian AAVs while unique surface
               features confer human antibody escape

                    Victoria E. Fielding, Q. Yu, M. R. Lee, P. Chipman, KV Vliet, R. McKenna, M.     Boisvert, P. Tijssen and M. Agbandje-McKenna

12:30 pm - 2:30 pm : Lunch

2:30 pm - 3:50 pm : Session 3A. Host - Virus Interactions

Chairpersons: Els Henckaerts and David Pintel

  • O-9     AAVR: a Protein Receptor Essential for AAV Cell Entry; Glycans in Attachment

                   N. Meyer, S. Pillay, Q. Xie, O. Davulcu, A. Puschnik, J. Diep, Y. Ishikawa, L. Jae, J. Wosen, C. Nagamine, A. Noble, S. Stagg ,
                   JE. Carette and Michael S. Chapman

  • O-10     Ambidensovirus transcystosis across the intestinal barrier requires interaction with glycosylated molecules

                      Anne-Sophie Gosselin Grenet, L. Gasmi, L. Pigeyre, M. Ravallec, T. Dupressoir and M. Ogliastro

  • O-11     Cellular Uptake of Parvovirus B19 - From Basic Research to Virus Mimicry

                      Remo Leisi, C. Ros and C. Kempf

  • O-12     Insights into the AAVrh.10 Capsid Structure and the Identification of a Potential Glycan Receptor

                     Mario Mietzsch, VV. Kim, L. Bridget, M. Janssen, F. Bröcker, G. Cardone, R.    McKenna, R. Crystal, J. Wilson, T. Baker,
                     PH Seeberger, R. Heilbronn, and M. Agbandje-McKenna

3:50 pm - 4:40 pm : Coffee Break & Poster Session

4:40 pm - 5:40 pm : Session 3B. Host - Virus Interactions

Chairpersons: Els Henckaerts and David Pintel

  • O-13     Parvovirus oncotropism results from a tight interplay with the PDK1_PKC_PKB signaling cascade

                      Jürg P.F. Nüesch, S. Bär and J. Rommelaere

  • O-14     MVM exploits the cellular DNA-damage response to establish a novel p21- and Chk1-independent cell-cycle arrest
                 during infection

                     Matthew Fuller, I. Etingov, K. Majumder and D. Pintel

  • O-15     KAP1-mediated latency of AAV2 is released through the Inhibition of protein phosphatase PP1 by the AAV2 Rep proteins

                      Sarah Smith, S. Neil, RM Linden, H. Rowe and E. Henckaerts

5:30 pm - 6:30 pm : Poster Session

6:30 pm - 9:00 pm : Reception at the Fesch Museum - Visit of the Napoleonian's rooms

Tuesday 21 June 2016

8:30 am - 10:20 am : Session 4A. Virus Structure and Engineering

Chairpersons: Mavis Agbandje-Mckenna and Jose M. Almendral

  • O-16     Evolution as a guide to understanding the structure-function relationship of AAV

                      Luk H. Vandenberghe

  • O-17     Development of AAV vectors with transduction activity in secretory epithelia

                      Giovanni Di Pasquale, WD. Swaim, T. Sheikh, S. Afione and JA. Chiorini.

  • O-18     New chimeric gene therapy vectors based on four different mammalian bocaviruses

                     Julia Fakhiri, M. Schneider, S. Kailasan, M. Meister, M. A. McKenna, Z. Yan and J. Qiu, D. Grimm

  • O-19     DARPins as flexible tool for cell surface AAV targeting

                      Jessica Hartmann, R. Freiling, R. Münch, S. Beyer, J. Koch, M. Seeger, K. Khodosevich, D. Garcia, H. Monyer and CJ. Buchholz

  • O-20     Fine tuning of transduction efficiency of rAAV vectors via modulation of capsid composition

                     O. Kondratov, D. Marsic, M. Mietzsch, R. Heilbronn and Sergei Zolotukhin

10:20 am - 11:10 am : Coffee Break & Poster Session

11:10 am - 12:30 pm : Session 4B. Virus Structure and Engineering

Chairpersons: Regine Heilbronn and Sergei Zolotukhin

  • O-21     Encapsidation of DNA in recombinant adeno associated virus like particles produced in the yeast Saccharomyces cerevisiae

                     Tiziana Cervelli, I. Iaia and A. Galli

  • O-22     Developing and characterizing AAV9 immune escape variants

                     J. Kennon Smith, Y-S. Tseng, M. Kaplan, L. Rao, R. McKenna, S. Zolotukhin, B. J. Byrne, A. Asokan, and M. Agbandje-McKenna

  • O-23     Structural Studies into the Thermostability of Novel In Silico Reconstructed Ancestral AAV Particles

                     Simon Pacouret, A. Maurer, H. Turunen, R. Xiao, E. Andre-Mateos, T. Barungi and LH Vandenberghe.

  • O-24     Next Generation of AAV Serotype Vectors for Human Gene Therapy: An Update

                     C. Lin, RW. Herzo, G. Ga and Arun Srivastava

12:30 pm - 2:30 pm : Lunch

2:30 pm - 3:50 pm : Session 3C. Host - Virus Interactions

Chairpersons: Maija Vihinen-Ranta and Michael Kann

  • O-25     The Minute Virus of Canines NP1 protein controls access to the viral capsid genes  via its role in RNA processing

                      O. Fasina, Y. Dong, S. Stupps and David Pintel

  • O-26     Short DNA Hairpins Generate Self-complementary Adeno-associated Virus   Genomes by a template-switching Mechanism

                     J. Xie, Q. Mao, R. He, PW Tai, J. Ai, Q. Su, Y. Zhu, H. Ma, J. Li, D. Wang, Z. Gao, M. Li, L. Zhong, H. Zhou, and G. Gao

  • O-27     Mutants at the 2-fold interface of AAV2 structural proteins suggest a role in viral transcription for AAV capsids

                     F. Aydemir, M. Salganik, J. Resztak, J. Singh, A. Bennett, M. Agbandje-McKenna and Nicholas Muzyczka

  • O-28     AAV2 VP3 Capsid Protein is an Auto-Catalytic Protease

                     Robert McKenna, A. Bennett, J. Kurian, S. Patel, M. Salganik and N. Muzyczka, M. Agbandje-McKenna

3:50 pm - 4:40 pm : Coffee Break & Poster Session

4:40 pm - 6:00 pm : Session 3D. Host - Virus Interactions

Chairpersons: Anne-Sophie Gosselin-Grenet and Carlos Ros

  • O-29     VP1 Dependent External Protease Activity in Adeno-Associated Virus Serotype 5 Capsids

                     Justin Kurian, A. Bennette, N. Muzyczka, R. McKenna and M. Agbandje-McKenna

  • O-30     Restricted siRNA screen reveals differential effects of cellular proteins on gene expression from single-stranded and
                 double-stranded AAV2 vectors

                     Francesca Daniela Franzoso, A. Yakimovich, K. Tobler, A. Man, R. Vogel, U. Greber, M.       Ackermann and C. Fraefel

  • O-31     Structural determinants of AAV Rep68 complex formation with with ssDNA

                     Carlos R. Escalante, V. Santosh, F. Zarate-Perez and F. Musayev

  • O-32     Point Mutations in Non-structural Coding Sequences of H-1 Rat Parvovirus and Consequences for Viral Fitness

                     H. Hashemi, N. Weiß, C. Geiß, J. Pilet, A. Stroh-Dege, AL Condurat, C Cornet Bartolomé, J. Rommelaere, N. Salomé and Christiane Dinsart

7:00 pm - 10:30 pm : Boat Tour to the Sanguinaires Islands

Wine tasting and buffet on board. Music Festival in town

Wednesday 22 June 2016

8:30 am - 10:20 am : Session 4A. Clinical parvovirology

Chairpersons: Maria Söderlund-Venermo and John Chiorini

  • O-33     Induction of an immune-active tumor microenvironment in recurrent glioblastoma multiforme patients
                 treated with H-1 parvovirus

                      A. Angelova, B. Leuchs, A. Just, M. Roscher, D. Capper, J. Hajda, K. Geletneky and Jean Rommelaere

  •  O-34    Oncolytic parvovirus H-1PV and the BH3 mimetic ABT-737 synergize against solid tumours

                     Antonio Marchini, J. Li, M. Fischer, L. Schroeder, L. Rausch and J. Rommelaere

  • O-35     Active human parvovirus B19 infection and phenotypic peculiarities of arthritis synovial fibroblasts

                     Valerie Groma, S. Skuja, M. Tarasovs, P. Studers, O. Teteris, A. Kadisa - S. Chapenko  and M. Murovska

  • O-36     Comparative analysis of the capsid structure and stability of true-type AAV2, a neurotropic AAV2 variant isolated
                 from children, with wild-type AAV2

                     Antonnette Bennett, J. Tordo, K. Moss, J. Hull, M. Linden, E. Henckaerts and M. Agbandje-McKenna

  • O-37     Gene therapy for treatment of temporal lobe epilepsy

                     AS Agostinho, M. Mietzsch, L. Zangrandi, C. Schwarzer and R. Heilbronn

10:20 am - 11:10 am : Coffee Break & Poster Session

11:10 am - 12:30 pm : Session 4B. Clinical parvovirology

Chairpersons: Susan Hafenstein  & Cornel Fraefel

  • O-38     Structure and Function Characterization of LuIII for the Development of New Brain Tumor Targeted Therapies

                     Nikéa Pittman, M. Janssen, L. Geilen, A. Misseldine, R. McKenna, T. Baker, S. Cotmore, P. Tattersall and M. Agbandje-McKenna

  • O-39     Modifying the AAV capsid for increased transduction following intravitreal injection

                     Sanford L. Boye, A. Bennett, S. Choudhury, D. Marsic, KT McCullough, J. Peterson, P. Gamlin , S. Zolotukhin,
                     M. Agbandje-McKenna and SE. Boye

  • O-40     Accurate diagnosis of human bocavirus 1 infection by RT-PCR, qPCR and serology

                     M. Xu, B. Arku, J. Koskinen, T. Jartti, K. Hedman and Maria Söderlund-Venermo

  • O-41     A single intravenous injection of a novel AAV micro-dystrophin vector resulted in extended amelioration of muscle
                disease in the canine model of Duchenne muscular Dystrophy

                    CH. Hakim, X. Pan, K. Kodippili, T. Blessa, HT Yang, G. Yao, S. Leach, C. Emter, Y. Yue, K. Zhang, SX Duan, N. Wasala,
                    G. Jenkins, CR. Legg, JS. Schneider, N. Yang, JS Chamberlain and Dongsheng Duan

12:30 pm - 2:30 pm : Lunch

2:30 pm - 3:50 pm : Session 4C. Host - Virus Interactions

Chairpersons: Christiane Dinsart and Michael Linden

  • O-42     Correlation of parvovirus-mediated nuclear envelope break-down with transduction using
                 EGFP-expressing AAV2 in individual cells

                     M. Legros, K. Snoussi, G. Di Pasquale, JA Chiorini and Michael Kann

  • O-43     Cellular challenges in parvovirus infection: nuclear import and chromatinization

                     E. Mäntylä, J. Chacko, CR Parrish, M. Kann, J. Timonen, K. Viiri, E. Gratton and Maija Vihinen-Ranta

  • O-44     Protein domains and postranslational modifications of the capsid subunits regulating MVM life cycle

                     J. Gil-Ranedo, E. Hernando, N. Bayat, N. Valle, L. Riolobos, B. Maroto and José M. Almendral

  • O-45     Role and Structural Requirements for AAP in AAV Capsid Assembly

                     Anna C. Maurer , S. Pacouret and LH. Vandenberghe

3:50 pm - 4:40 pm : Coffee Break & Poster Session

4:40 pm - 6:10 pm : Session 4D. Host - Virus Interactions

Chairpersons: Christiane Dinsart and Michael Linden

  • O-46     The role of glucocorticoid receptor signaling in adeno-associated virus 2 infection

                     Chen Ling, Y. Lu, J. Li, D. Zhang, C. Ling and A. Srivastava

  • O-47     Implication of calcium signaling during early stages of densovirus infection

                     Adeline Kerviel, T. Dupressoir, AQ Gosselin-Grenet and M. Ogliastro

  • O-48     The SAT protein of ungulate protoparvovirus-1 accelerate viral spreading   through irreversible ER stress induction

                     István Mészáros, R. Tóth, P. Tijssen and Z. Zádori

5:40 pm - 6:10 pm : Cloture Session

Peter Tattersall and Peter Beard

8:00 pm - 11:59 pm : Cocktail and Gala Dinner at the Palais des Congres

Thursday 23 June 2016

8:00 am - 7:00 pm : Tour to Bonifacio